Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection.

Dong, Xintong; Limjunyawong, Nathachit; Sypek, Elizabeth I; Wang, Gaofeng; Ortines, Roger V; Youn, Christine; Alphonse, Martin P; Dikeman, Dustin; Wang, Yu; Lay, Mark; Kothari, Ruchita; Vasavda, Chirag; Pundir, Priyanka; Goff, Loyal; Miller, Lloyd S; Lu, Wuyuan; Garza, Luis A; Kim, Brian S; Archer, Nathan K; Dong, Xinzhong.

Immunity ; 55(9): 1645-1662.e7, 2022 09 13.

Artigo em Inglês | MEDLINE | ID: mdl-35882236

2.

Human Enteric α-Defensin 5 Promotes Shigella Infection by Enhancing Bacterial Adhesion and Invasion.

Xu, Dan; Liao, Chongbing; Zhang, Bing; Tolbert, W David; He, Wangxiao; Dai, Zhijun; Zhang, Wei; Yuan, Weirong; Pazgier, Marzena; Liu, Jiankang; Yu, Jun; Sansonetti, Philippe J; Bevins, Charles L; Shao, Yongping; Lu, Wuyuan.

Immunity ; 48(6): 1233-1244.e6, 2018 06 19.

Artigo em Inglês | MEDLINE | ID: mdl-29858013

3.

Flagella-driven motility is a target of human Paneth cell defensin activity.

Akahoshi, Douglas T; Natwick, Dean E; Yuan, Weirong; Lu, Wuyuan; Collins, Sean R; Bevins, Charles L.

PLoS Pathog ; 19(2): e1011200, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-36821624

4.

Human defensin-inspired discovery of peptidomimetic antibiotics.

Luo, Gan; Zhang, Jue; Wang, HanBin; Sun, YaQi; Cheng, BaoLi; Xu, ZhiPeng; Zhang, Yan; Li, Hui; Lu, WuYuan; Nemeth, Elizabeta; Ganz, Tomas; Fang, XiangMing.

Proc Natl Acad Sci U S A ; 119(10): e2117283119, 2022 03 08.

Artigo em Inglês | MEDLINE | ID: mdl-35238683

5.

A heterodimer of α and ß hemoglobin chains functions as an innate anticancer agent.

Chelladurai, Maharrish; Xu, Dan; Izraely, Sivan; Ben-Menachem, Shlomit; Bengaiev, Roman; Sagi-Assif, Orit; Yuan, Weirong; Pasmanik Chor, Metsada; Hoon, Dave S; Lu, Wuyuan; Witz, Isaac P.

Int J Cancer ; 154(3): 561-572, 2024 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-37675956

6.

Evolution toward beta common chain receptor usage links the matrix proteins of HIV-1 and its ancestors to human erythropoietin.

Caccuri, Francesca; D'Ursi, Pasqualina; Uggeri, Matteo; Bugatti, Antonella; Mazzuca, Pietro; Zani, Alberto; Filippini, Federica; Salmona, Mario; Ribatti, Domenico; Slevin, Mark; Orro, Alessandro; Lu, Wuyuan; Liò, Pietro; Gallo, Robert C; Caruso, Arnaldo.

Proc Natl Acad Sci U S A ; 118(2)2021 01 12.

Artigo em Inglês | MEDLINE | ID: mdl-33372148

7.

Mouse α-Defensins: Structural and Functional Analysis of the 17 Cryptdin Isoforms Identified from a Single Jejunal Crypt.

Wang, Qingxia; Yang, Yilin; Luo, Gan; Zhou, Yang; Tolbert, William D; Pazgier, Marzena; Liao, Chongbing; Lu, Wuyuan.

Infect Immun ; 91(1): e0036122, 2023 01 24.

Artigo em Inglês | MEDLINE | ID: mdl-36472443

8.

Configuration-Specific Antibody for Bacterial Heptosylation: An Antiadhesion Therapeutic Strategy.

Li, Xiang; Liao, Chongbing; Xu, Yue; Lu, Qiu-He; Chen, Si; Su, Li; Zou, Yan; Shao, Feng; Lu, Wuyuan; Zhang, Wei-Dong; Hu, Hong-Gang.

J Am Chem Soc ; 145(1): 322-333, 2023 01 11.

Artigo em Inglês | MEDLINE | ID: mdl-36542493

9.

Human defensins facilitate local unfolding of thermodynamically unstable regions of bacterial protein toxins.

Kudryashova, Elena; Quintyn, Royston; Seveau, Stephanie; Lu, Wuyuan; Wysocki, Vicki H; Kudryashov, Dmitri S.

Immunity ; 41(5): 709-21, 2014 Nov 20.

Artigo em Inglês | MEDLINE | ID: mdl-25517613

10.

Mechanism through Which Retrocyclin Targets Flavivirus Multiplication.

Jia, Xiaoying; Guo, Jiao; Yuan, Weirong; Sun, Lingling; Liu, Yang; Zhou, Minmin; Xiao, Gengfu; Lu, Wuyuan; Garzino-Demo, Alfredo; Wang, Wei.

J Virol ; 95(15): e0056021, 2021 07 12.

Artigo em Inglês | MEDLINE | ID: mdl-33980602

11.

Chiral Protein Supraparticles for Tumor Suppression and Synergistic Immunotherapy: An Enabling Strategy for Bioactive Supramolecular Chirality Construction.

Yan, Jin; Yao, Yu; Yan, Siqi; Gao, Ruqing; Lu, Wuyuan; He, Wangxiao.

Nano Lett ; 20(8): 5844-5852, 2020 08 12.

Artigo em Inglês | MEDLINE | ID: mdl-32589431

12.

Critical determinants of human neutrophil peptide 1 for enhancing host epithelial adhesion of Shigella flexneri.

Liao, Chongbing; Fang, Kun; Xiao, Jiu; Zhang, Wei; Zhang, Bing; Yuan, Weirong; Lu, Wuyuan; Xu, Dan.

Cell Microbiol ; 21(10): e13069, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-31218775

13.

A Hierarchical Peptide-Lanthanide Framework To Accurately Redress Intracellular Carcinogenic Protein-Protein Interaction.

Yan, Jin; Yan, Siqi; Hou, Peng; Lu, Wuyuan; Ma, Peter X; He, Wangxiao; Lei, Bo.

Nano Lett ; 19(11): 7918-7926, 2019 11 13.

Artigo em Inglês | MEDLINE | ID: mdl-31645103

14.

Human Enteric Defensin 5 Promotes Shigella Infection of Macrophages.

Xu, Dan; Liao, Chongbing; Xiao, Jiu; Fang, Kun; Zhang, Wei; Yuan, Weirong; Lu, Wuyuan.

Infect Immun ; 88(1)2019 12 17.

Artigo em Inglês | MEDLINE | ID: mdl-31611271

15.

Self-Assembly of Therapeutic Peptide into Stimuli-Responsive Clustered Nanohybrids for Cancer-Targeted Therapy.

He, Wangxiao; Wang, Simeng; Yan, Jin; Qu, Yiping; Jin, Liang; Sui, Fang; Li, Yujun; You, Weiming; Yang, Guang; Yang, Qi; Ji, Meiju; Shao, Yongping; Ma, Peter X; Lu, Wuyuan; Hou, Peng.

Adv Funct Mater ; 29(10)2019 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-32982625

16.

Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation.

Brook, Matthew; Tomlinson, Gareth H; Miles, Katherine; Smith, Richard W P; Rossi, Adriano G; Hiemstra, Pieter S; van 't Wout, Emily F A; Dean, Jonathan L E; Gray, Nicola K; Lu, Wuyuan; Gray, Mohini.

Proc Natl Acad Sci U S A ; 113(16): 4350-5, 2016 Apr 19.

Artigo em Inglês | MEDLINE | ID: mdl-27044108

17.

Defensins Potentiate a Neutralizing Antibody Response to Enteric Viral Infection.

Gounder, Anshu P; Myers, Nicolle D; Treuting, Piper M; Bromme, Beth A; Wilson, Sarah S; Wiens, Mayim E; Lu, Wuyuan; Ouellette, André J; Spindler, Katherine R; Parks, William C; Smith, Jason G.

PLoS Pathog ; 12(3): e1005474, 2016 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-26933888

18.

Role of HIV-1 matrix protein p17 variants in lymphoma pathogenesis.

Dolcetti, Riccardo; Giagulli, Cinzia; He, Wangxiao; Selleri, Marina; Caccuri, Francesca; Eyzaguirre, Lindsay M; Mazzuca, Pietro; Corbellini, Silvia; Campilongo, Federica; Marsico, Stefania; Giombini, Emanuela; Muraro, Elena; Rozera, Gabriella; De Paoli, Paolo; Carbone, Antonino; Capobianchi, Maria Rosaria; Ippolito, Giuseppe; Fiorentini, Simona; Blattner, William A; Lu, Wuyuan; Gallo, Robert C; Caruso, Arnaldo.

Proc Natl Acad Sci U S A ; 112(46): 14331-6, 2015 Nov 17.

Artigo em Inglês | MEDLINE | ID: mdl-26578780

19.

Differential Roles of Chemokines CCL2 and CCL7 in Monocytosis and Leukocyte Migration during West Nile Virus Infection.

Bardina, Susana V; Michlmayr, Daniela; Hoffman, Kevin W; Obara, Christopher J; Sum, Janet; Charo, Israel F; Lu, Wuyuan; Pletnev, Alexander G; Lim, Jean K.

J Immunol ; 195(9): 4306-18, 2015 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-26401006

20.

Antimicrobial peptides.

Lu, Wuyuan.

Semin Cell Dev Biol ; 88: 105-106, 2019 04.

Artigo em Inglês | MEDLINE | ID: mdl-29859256

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